B02 - Signals and substrates of cell death proteases in plant – microbe interactions
Regulated cell death (RCD) plays a major role in determining the outcome of plant-microbe interactions. Initiation and execution of RCD often involves proteolytic activity, however little is known about the signals that activate cell death proteases, their substrates that are cleaved or degraded during RCD, the immune signals that are released by dying cells, the response by surrounding cells, and how proteases contribute to specificity and execution of different plant cell death pathways. This project aims to characterise protease-substrate relationships underlying RCD and their consequences for plant-pathogen interactions.
Mooney, B. C., Mantz, M., Graciet, E, Huesgen, P. F. (2021) Cutting the line: manipulation of plant immunity by bacterial type III effector proteases. J Exp Bot doi:10.1093/jxb/erab095