A01 | PASPARAKIS
Mechanisms of cell death-induced inflammation
Research area A: Cell Death in inflammation and disease
Work in research area A focuses the regulation and function of cell death in organism a homeostasis and disease. Within this research area, 13 projects study how different forms of RCD are regulated, how dying cells are sensed by bystander cells and how this cross-talk triggers distinct tissue responses resulting in tissue repair or inflammation and disease.
A02 | GARCIA SAEZ & PASPARAKIS
Cross-talk between dying and bystander cells in vitro and in vivo: an optogenetics approach
A03 | HORNUNG
The role of metalloprotease activity in necroptosis driven inflammation
A04 | SCHMIDT
Molecular pathways of gasdermin pore formation and repair
A05 | VON KARSTEDT
Inflammatory signalling in ferroptotic cell death
A06 | LANGER
The role of mitochondria for cellular protection against ferroptosis
A07 | EMING
Control of macrophage cell death in skin homestasis and repair
A09 | BENZING & SCHERMER
Regulated cell death and kidney fibrosis as a consequence of mutation of cilia-associated genes
A10 | PELTZER
Cell death and inflammation modulated by the ubiquitin E3 ligase activities whin LUBAC in metabolic inflmmation
A11 | LATZ
NLRP10 inflammasome mediated anti-inflammation in immune signalling
A12 | WALCZAK
The role of ANKIB1 in regulating cell death in inflammation in immune signalling
A13 | ISING
Contribution of microglia cell death to tau pathology in Alzheimer's disease and other tauopathies
A14 | ODA
Immunological dissection of cell death-induced inflammation in human disease