Sun Z, Hornung V. (Review)
A critical role for palmitoylation in pyroptosis
Abstract
Three recent publications by Du et al.,1 Balasubramanian et al.,2 and Zhang et al.3 identified palmitoylation on cysteine 191/192 in gasdermin D as a key determinant of gasdermin D membrane translocation and oligomerization, ensuring efficient plasma membrane permeabilization during pyroptosis.
Read more at Mol Cell 2024 Jun 20