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A12 - The role of a new E3 ligase in regulating cell death and inflammation in immune signaling

Henning Walczak

Department of Biochemistry I, CECAD, University of Cologne
Contact: h.walczak(at)uni-koeln.de
For more information visit: Walczak lab

Abstract

This project is funded within the 2nd funding period of the SFB 1403, starting from 2024

Recent Publications

2025

Ros U, Martinez-Osorio V, Valiente PA, Abdelwahab Y, Gojkovic M, Shalaby R, Zanna S, Saggau J, Wachsmuth L, Nemade HN, Zoeller J, Lottermoser H, Chen YG, Ibrahim M, Kelepouras K, Vasilikos L, Bedoya P, Espiritu RA, Müller S, Altmannova V, Tieleman DP, Weir J, Langer J, Adam M, Walczak H, Wong WW, Liccardi G, Mollenhauer M, Pasparakis M, Peltzer N, García-Sáez AJ. MLKL activity requires a splicing-regulated, druggable intramolecular interaction. Mol Cell. 2025 Apr 3:S1097-2765(25)00259-X.  doi: 10.1016/j.molcel.2025.03.015. Epub vor dem Druck. PMID: 40209701

Project A12 Publications 2nd Funding Period 2024 - 2027

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