B03 - Cell death regulation and function in plant-fungal symbiosis
Alga Zuccaro
Department of Botany, CEPLAS, University of Cologne
Contact: azuccaro(at)uni-koeln.de
For more information visit: Zuccaro lab
Abstract
Colonisation of plant roots by the beneficial fungal endophyte Serendipita indica involves a biotrophic phase and a host cell death phase characterised by production of deoxyadenosine (dAdo). This project will dissect plant immunity and cell death mechanisms induced by dAdo during fungal accommodation and the associated signalling pathways. We aim to elucidate how manipulation of particular plant cell death processes interferes with fungal accommodation and beneficial effects and whether these converge on a common core machinery for cell death control in plant roots.
Recent Publications
Dunken N, Widmer H, Balcke GU, Straube H, Langen G, Charura NM, Saake P, De Quattro C, Schön J, Rövenich H, Wawra S, Khan M, Djamei A, Zurbriggen MD, Tissier A, Witte CP, Zuccaro A. A nucleoside signal generated by a fungal endophyte regulates host cell death and promotes root colonization. Cell Host Microbe. 2024 Nov 19:S1931-3128(24)00406-2. doi: 10.1016/j.chom.2024.10.020. Epub ahead of print. PMID: 39603244.
Charura N, Llamas E, De Quattro C, Vilchez D, Nowack MK, Zuccaro A. Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana. Elife. 2024 Nov 12;13:RP96266. doi: 10.7554/eLife.96266. PMID: 39531016; PMCID: PMC11556792.